The Health Ethics Committee (HEC) plays a vital role in ensuring ethical practices within clinical trials and health research. Its primary function is to provide opinions before clinical trials commence, addressing any requested issues related to medical products and devices. The committee evaluates research proposals in the health sector, considering ethical aspects and data protection to safeguard participant safety and rights. It collaborates closely with the Research Ethics Committee at the University of Malta, ensuring compliance with regulations and the Data Protection Act. Additionally, when relevant issues arise, the committee advises the Minister or Director General on matters related to public health regulation.